Working with WPF Frame using C# and XAML

<Window x:Class="FrameSample.Window1"  
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"  
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"  
    Title="Window1" Height="300" Width="300">  
    <Grid>          
        <TextBlock>Outside area of frame</TextBlock>  
        <Frame Source="Page1.xaml">              
        </Frame>  
    </Grid>  
</Window>

navigate to a URI in a WPF Frame

<Window x:Class="FrameSample.Window1"  
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"  
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"  
    Title="Window1" Height="300" Width="300">  
    <Grid>  
        <TextBlock>Outside area of frame</TextBlock>  
        <Frame Name="FrameWithinGrid" >  
        </Frame>  
        <Button Height="23" Margin="114,12,25,0"   
                Name="button1" VerticalAlignment="Top" Click="button1_Click">Navigate to C# Corner  
        </Button>  
    </Grid>  
</Window>

private void button1_Click(object sender, RoutedEventArgs e)  
{  
    FrameWithinGrid.Navigate(new System.Uri("Page1.xaml",  
             UriKind.RelativeOrAbsolute));  
}

navigate to an external website URL and opens the ASPX page within a Frame

FrameWithinGrid.Source = new Uri("http://www.c-sharpcorner.com/Default.aspx", UriKind.Absolute);

this code first creates a NavigationWindow and then sets its Source to a URI

NavigationWindow window = new NavigationWindow();  
Uri source = new Uri("http://www.c-sharpcorner.com/Default.aspx", UriKind.Absolute);  
window.Source = source; window.Show();

private void NavigationViewItemHome_OnClick(object sender, RoutedEventArgs e)
{
    FrameMain.Navigate(new PageItems());
}

References
https://www.c-sharpcorner.com/UploadFile/mahesh/using-xaml-frame-in-wpf857/
https://www.youtube.com/watch?v=YoZcAx_0rNM