In /etc/NetworkManager/NetworkManager.conf comment out the line dns=dnsmasq
sudo nano /etc/NetworkManager/NetworkManager.conf
[main] plugins=ifupdown,keyfile,ofono #dns=dnsmasq
and restart the NetworkManager service.
sudo restart network-manager
sudo rm -f /etc/resolv.conf # Delete the symbolic link
sudo nano /etc/resolv.conf # Create static file
# Content of static resolv.conf nameserver 208.67.220.220 nameserver 208.67.220.222
References
http://askubuntu.com/questions/690511/how-to-change-dns-in-ubuntu-15-10